Figure 8
From: The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb
OTX015 increases CDK9 T-loop phosphorylation in Jurkat C11 cells.
After Jurkat C11 cells were treated with different concentrations of OTX015 or JQ1 as indicated for 24 h, total CDK9 (A), Cyclin T1 (B) levels and the extent of CDK9 phosphorylation on Thr186 (pT186) (C) were determined by Western Blotting.
