Figure 8 | Scientific Reports

Figure 8

From: Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing

Figure 8

H19 knockdown decreases the formation of capillary-like structures.

HUVEC were transfected with an antisense LNA GapmeRs specific for H19 or with negative control. The ability to form capillary like structures was quantified by matrigel-assay 48h after transfection. (a) The bar graph shows a significant reduction of the number of branches upon H19 knockdown versus control (n = 9, ***p < 0.001). (b) Representative phase-contrast images of the organization into capillary-like structures are shown.

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