Figure 6: HCCR silencing repressed gastric cancer progression in vivo and sensitized gastric cancer cells to 5-FU. | Scientific Reports

Figure 6: HCCR silencing repressed gastric cancer progression in vivo and sensitized gastric cancer cells to 5-FU.

From: Targeting HCCR expression resensitizes gastric cancer cells to chemotherapy via down-regulating the activation of STAT3

Figure 6

HCCR-shRNA and negative control cells were subcutaneously injected into nude mice that were/were not treated with 5-FU. (A) The volume and weight of the tumours are indicated by the mean values (±s.d.) of six mice from each group, *P < 0.05, significant difference from control cells. (B) The sections were stained with antibodies against human HCCR, p-STAT3 and cleaved caspase-3. The sum densities were calculated and analysed with IPP 6.0. Columns are means (±s.d.) of quintuplicate determinations of six mice from each group. *P < 0.05.

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