Figure 2 | Scientific Reports

Figure 2

From: Procaspase-9 induces its cleavage by transnitrosylating XIAP via the Thioredoxin system during cerebral ischemia-reperfusion in rats

Figure 2

The time course of transnitrosylation from procaspase-9 to XIAP and the cleavage of procaspase-9 induced by ischemia-reperfusion (I/R).

(A) The time course of S-nitrosylated XIAP and procaspase-9 and the cleavage of procaspase-9 (cleaved caspase-9) in the rat hippocampal CA1 derived from sham-treated animals or rats subjected to 15 min ischemia at various time points after reperfusion. (B) Bands were quantified and the intensities were presented as fold-increase vs. the sham group. Data were the means ± S.D. from four independent experiments (n = 4). *P < 0.05 vs. the sham group.

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