Figure 5 | Scientific Reports

Figure 5

From: Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus

Figure 5

Immunomodulatory properties of FP and SF-MSCs after stimulation with IFN-γ (error bars indicate SEM).

(a) Both FP and SF-MSCs (n = 3) inherently produce HLA-G in control conditions (82.7% ± 5.1 and 64.0% ± 3.4 respectively), as well as following treatment with 25 ng/ml (73.8% ± 11.2 and 52.4% ± 12.5 respectively) and 500 ng/ml IFN-γ (79.7% ± 8.3 and 5.2% ± 14.9 respectively). (b) Cropped image of a representative western blot indicating the production of IDO by FP-MSCs and SF-MSCs after stimulation with IFN-γ, but not in untreated controls, a full-length blot is presented in Supplementary Figure S1.

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