Table 2 Results of the hierarchical regression analysis for the influence of cell source, passage number and donor on doubling time of matched FP- and SF-MSCs.

From: Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus

Factor

Fixed/Random effect

Coefficient or SD (days)

p-value

Cell source (SF)

Fixed

8.3 (6.1–10.4)

<0.001

Passage number

Fixed

1.4 (0.8–2.0)

<0.001

Passage by donor

Random

0.54 (0.19–1.1)

0.004

  1. Note: Coefficients and standard deviation (SD) based on a linear mixed effect model. P-values are from Wald tests (fixed effects) and likelihood ratio tests (random effects).
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