Table 1 Differentiation potential and angiogenic support function hESC-derived perivascular progenitors and primary perivascular cells.

From: A novel lineage restricted, pericyte-like cell line isolated from human embryonic stem cells

Cell Source

Cell Type

Adipogenic and Osteogenic

Differentiation Potential

Angiogenic Support Function Assayed

by In VitroTube Formation

Oil Red O Staining

Alizarin Red Staining

Day 1

Day 6

Human

embryonic

stem cells

017-PC-A

−

−

+

−

017-PC-M

−

−

++

++

017-PC-O

−

+

+

−

Bone Marrow

BM-MSC

+

+

+

−

Placental

Pl-PCs

−

+

+

−

  1. Each cell type was evaluated for osteogenic and adipogenic potential; cells capable of differentiating down these linages are marked (+). Each cell type was evaluated for angiogenic support function as monitored by tube network formation for 6 days of cell culture (Figs 5, 6 and S6). Cells co-cultured with human umbilical vein endothelial cells showed (−), minimal (+) or extensive (++) tube network formation over multiple days.