Figure 1: Results of gap pre-pulse inhibition of acoustic startle. | Scientific Reports

Figure 1: Results of gap pre-pulse inhibition of acoustic startle.

From: Effects of long-term salicylate administration on synaptic ultrastructure and metabolic activity in the rat CNS

Figure 1

(a) Effects of salicylate in gap pre-pulse inhibition of acoustic startle (GPIAS) values. The chronic treatment (n = 6 rats) group had a significant decrease in GPIAS values compared with the saline group (n = 6 rats) at 12 (chronic = 13.38 ± 4.61, saline = 42.19 ± 14.65, *p < 0. 05) and 16 kHz (chronic = 14.60 ± 6.50, saline = 41.33 ± 14.65,*p < 0.05), but not at 6 kHz (chronic = 44.18 ± 7.98, saline = 44.92 ± 15.34, p > 0.05). There were no significant differences in the GPIAS values among the acute treatment (n = 6 rats), wash-out (n = 6 rats), and saline groups (p > 0.05). (b) Effects of salicylate on pre-pulse inhibition (PPI) values. There were no significant differences in the PPI values among the four groups at 6, 12 and 16 kHz.

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