Figure 2: Corresponding transaxial (1^st and 2^nd columns) and sagittal (3^rd column) images obtained from microPET, fused CT/microPET (coronal, 4^th column) of a rat.

(a–d) MicroPET brain images of rats from the saline group (n = 6 rats). (e–h) The mean SUVs in the acute treatment group (n = 6 rats) were significantly greater than those in the other three groups. (i–l) The mean SUVs in the chronic treatment group (n = 6 rats) were greater than those in the wash-out (n = 6 rats) and saline groups. (m–p) MicroPET brain images of rats from the wash-out group. There was no significant difference in the mean SUVs between the saline and wash-out groups. Dotted areas indicate the inferior colliculus (IC, 1^st column), auditory cortex (AC, 2^nd column, lateral areas), hippocampus (HP, 2^nd column, medial areas), amygdala (AMY, 3^rd column, upper areas), and cerebellum (CRB, 3^rd column, lower areas) at the corresponding levels (marked in the 4^th column). All rats were imaged in the prone position. PET images of average brain activity from the time of 18F-FDG injection until 40 min later are displayed with identical colour scales (right). Ant, anterior; Post, posterior; R, right; L, left.