Figure 4 | Scientific Reports

Figure 4

From: Genipin cross-linked decellularized tracheal tubular matrix for tracheal tissue engineering applications

Figure 4

Macroscopic appearance of an explanted scaffold.

The native trachea, decellularized trachea, genipin-crosslinked decellularized trachea and glutaraldehyde-crosslinked decellularized trachea matrices after being implanted in rats for 0 (A), 7 (B), 15 (C) and 30 (D) days. The native trachea (E) and glutaraldehyde-crosslinked decellularized trachea matrices (H) exhibited a thick fibrous capsule with a large amount of pus and a damaged trachea 30 days after implantation. The optimal decellularized trachea (F) and genipin-crosslinked decellularizedtracheae (G) were covered by a thin capsule and neovascularized on the surface 30 days after implantation.

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