Table 1 Clinicopathological variables and miR-183/182/96 expression in 131 breast cancer patients.

Characteristics	Total (n = 131)	miR-183 High/Low	P value	miR-182 High/Low	P value	miR-96 High/Low	P value
Characteristics	Total (n = 131)	(73/58)	P value	(74/57)	P value	(86/45)	P value
OS			0.000*		0.000*		0.022*
Present	97	43/54		42/55		58/39
Absent	34	30/4		32/2		28/6
DFS			0.000*		0.004*		0.011*
Present	93	42/51		45/48		55/38
Absent	38	31/7		29/9		31/7
Age (years)			0.439		0.084		0.410
<50	81	43/38		41/40		51/30
>=50	50	30/20		33/17		35/15
Menopause			0.842		0.071		0.822
Yes	60	34/26		39/21		40/20
No	71	39/32		35/36		46/25
Tumor size (cm)			0.809		0.969		0.129
=<2	37	20/17		21/16		28/9
>2	94	53/41		53/41		58/36
LNMET			0.745		0.592		0.089
Yes	77	42/35		42/35		46/31
No	54	31/23		32/22		40/14
TNM stage			0.012*		0.018*		0.020*
I–II	72	33/39		34/38		41/31
III–IV	59	40/19		40/19		45/14
Local relapse			0.025*		0.028*		0.849
Yes	8	8/0		8/0		6/2
No	123	65/58		66/57		80/43
Distant metastasis			0.000*		0.001*		0.033*
Yes	32	27/5		26/6		26/6
No	99	46/53		48/51		60/39
ER status			0.635		0.180		0.752
Positive	49	26/23		24/25		33/16
Negative	82	47/35		50/32		53/29
PR status			0.725		0.115		0.959
Positive	52	28/24		25/27		34/18
Negative	79	45/34		49/30		52/27
HER-2 status			0.553		0.501		0.784
Positive	22	11/11		11/11		15/7
Negative	109	62/47		63/46		71/38
P53 status			0.745		0.590		0.014*
Positive	77	42/35		45/32		44/33
Negative	54	31/23		29/25		42/12

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