Figure 3: Effect of the cationic polymers on tumour growth in vivo. | Scientific Reports

Figure 3: Effect of the cationic polymers on tumour growth in vivo.

From: Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy

Figure 3

(A) The average tumour weight after the mice were treated with cationic polymers for 14 days; (B) tumour growth curves from mice that received intratumoural injection of saline, C-dextran, PEI or dextran. (C) Representative images of tumour samples harvested from animals in each treatment cohort (scare bar: 1 cm). (D) Survival rate of tumour-bearing mice treated with saline, C-dextran, PEI or Dextran. (E) H&E histological assessment of the tumour sections from mice that received saline, C-dextran, PEI or dextran (scale bar: 100 μm). (F) The mean spleen weights on day 14 after treatment with cationic polymers. (G) Representative images of spleens harvested from animals in each treatment cohort (scare bar: 1 cm; n  = 8–10 mice per group; *P ≤ 0.05 versus saline).

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