Table 2 Significant interaction effect, between-group and within-group differences in ReHo-seed (vmPFC) functional connectivity analyses.

From: Dynamic Changes of Functional Pain Connectome in Women with Primary Dysmenorrhea

Contrast

Region

BA

Size

t score

Coordinate

x

y

z

left side ReHo-seed (−6, 50, 4)

Interaction

 PDMΔ(MENS-POV) > CONΔ(MENS-POV)

SMA/MCC

6

539

3.95

2

−6

50

Between-group planned contrast

 MENS: PDM > CON

SFG

6

388

3.97

−14

24

58

dmPFC

9

384

3.94

−10

48

28

 MENS: CON > PDM

dACC

32

374

4.2

2

20

32

 POV: PDM > CON

dmPFC/DLPFC

8

952

4.24

−12

30

40

VPL/angular

39

372

3.85

−42

−68

48

 POV: CON > PDM

pACC

24

823

4.28

0

38

10

2

22

28#

Between-phase planned contrast

 CON: POV > MENS

SMA

6

580

4.46

−12

−12

54

right side ReHo-seed (6, 62, 22)

Between-group planned contrast

 POV: CON > PDM

IFG

–

335

5.06

46

20

6

pACC

32

691

3.99

4

40

8

Between-phase planned contrast

 PDM: POV > MENS

pons

–

325

4.58

12

−38

−34

  1. Peak coordinates refer to Montreal Neurological Institute space. Significance thresholded at the uncorrected voxel level p = 0.005 followed by the FWE-corrected cluster level p = 0.05.
  2. SMA, supplementary motor area; MCC, midcingulate cortex; SFG, superior frontal gyrus; dmPFC, dorsomedial prefrontal cortex; dACC, dorsal anterior cingulate cortex; DLPFC, dorsolateral prefrontal cortex; VPL, ventral parietal lobe; pACC, pregenual anterior cingulate cortex; IFG, inferior frontal gyrus (see Table 1 for other abbreviation details) #the second highest peak, almost the same location with the highest peak in the MENS phase.