Figure 5: After injection, Cy3-labeled Ago299-5p is distributed throughout the brain tissues. | Scientific Reports

Figure 5: After injection, Cy3-labeled Ago299-5p is distributed throughout the brain tissues.

From: MiR-299-5p regulates apoptosis through autophagy in neurons and ameliorates cognitive capacity in APPswe/PS1dE9 mice

Figure 5

(a) 9-month-old APPswe/PS1dE9 mice were injected with different doses of Cy3-labeled Ago299-5p into the third ventricle (n = 3). Fluorescence of Cy3 was disseminated throughout the hippocampi and surrounding tissues after injection with 0.5 nmol for 24 h. Scale bar = 250 μm. (b) Cy3-labeled Ago299-5p was absorbed into MAP2-positive neurons and GFAP-positive glial cells. Scale bar = 25 μm.

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