Figure 4: Characterising the DARC dependence of P. knowlesi merozoites for the invasion of human and macaque normocytes.
From: Invasion characteristics of a Plasmodium knowlesi line newly isolated from a human
Inhibition of P. knowlesi (UM01 and A1-H.1 lines) invasion into human (Hu) and macaque (Mc) normocytes by MAb Fy6 and anti-Fyb (Duffy negative human blood was used as a positive control). Bars show the percentage grand median inhibition levels normalised to the Ab-free control of each independent experiment for the UM01 line. The effect of MAb Fy6 and anti-Fyb in invasion inhibition in both human and macaque blood was compared using a 1Way ANOVA and Tukey’s Multiple Comparison Tests.
