Figure 4
From: Gene-set Analysis with CGI Information for Differential DNA Methylation Profiling
(A) Plots of pathway effects. (A) Scores of strength for the 10 competing pathways in the UKOPS study. (B) Boxplots of posterior samples under each pathway for 32 lung adenocarcinoma patients. A box beyond zero implies a large probability of hypermethylation; while a box below zero indicates a large probability of hypomethylation. (C) Probability density plot for each of the four pathway effects. Most of the red curve for the effect of axonal guidance signaling pathway locates in the positive part, indicating a strong hypermethylation effect for this pathway. (D) Boxplots of posterior samples in each pathway in the breast cancer study.
