Table 2 Gene symbols of the 61 DMGs identified in the pathways in cancer, and 14 DMGs identified in the cell cycle pathway.

From: Gene-set Analysis with CGI Information for Differential DNA Methylation Profiling

Gene symbol

Previously reported (35 genes)

 In both pathways

CCND1 a , CDKN2A, CDKN2B, CDK2, CDKN1A, SMAD2

 In pathways in cancer

APPL1, BAX, BCL2 a , DCC, EGFR, ERBB2 a , EGF23, EGF3, EGF4, EGF5, EGF8, FOXO1, FRAP1 b , IL6, KITLG, LAMB2, MMP2, MMP9, PTEN, PTK2, RARB a , RUNX1 b , STAT3 b , STAT5A, TGFBR1, WNT2

 In cell cycle pathway

ATM b , CCNB2 b , CHEK2 b

Previously unknown (33 genes)

 In both pathways

CCNA1

 In pathways in cancer

ARNT2, BIRC2, CSF3R, CUL2, CYCS, FASLG, FGF10, FGF12, FGF17, FGF19, FZD10, FZD8, HSP90AB1, JUP, LAMA1, LAMA4, NKX3-1, PIK3CD, PRKCB, PITCH2, RALGDS, RASSF5, RXRB, SMO, SPI1, WNT10A, WNT11, WNT3A

 In cell cycle pathway

ESPL1, MCM4, TFDP1, YWHAQ

Previously reported DMGs in other pathways (11 genes)

 

COL1A1, COL6A1 b , CR1, GSTP1, IGFBP3, KDR, MOS, PGR, PLAU, PPP2R1B, TP73

  1. aThese genes contain both hyper- and hypo-methylated probes.
  2. bThese genes contain probes that are more hypermethylated in cases than in controls.