Table 3 Genes with large probabilities of hypermethylation or hypomethylation under the axonal guidance pathway in the lung cancer study.

From: Gene-set Analysis with CGI Information for Differential DNA Methylation Profiling

 

Difference in DNAm

Difference in Gene Exp

 

Mean

SD

Mean

SD

Pr(hypermethylation)

 ABLIM1

>0.99

0.14

0.11

−0.82

0.54

 DCC

>0.99

0.14

0.16

−0.36

0.28

 EFNA2

0.96

0.07

0.13

−0.05

0.22

 EFNB1

0.98

0.07

0.08

−0.27

0.38

 EPHA5

0.99

0.08

0.09

−0.12

0.30

 EPHA8

0.96

0.06

0.07

0.09

0.23

 LIMK1

0.99

0.10

0.12

0.36

0.24

 LRRC4

0.98

0.11

0.15

−0.29

0.40

 NTNG1

0.96

0.06

0.07

−0.67

0.47

 PAK2

>0.99

0.13

0.13

−0.08

0.47

 PAK7

0.97

0.08

0.12

0.08

0.13

 PLXNB1

0.99

0.13

0.17

<0.01

0.13

 SEMA3G

0.99

0.09

0.08

−1.72

1.35

 SEMA3E

0.91

0.04

0.08

−1.22

1.47

 SLIT2

0.93

0.05

0.10

−1.62

1.11

 SLIT3

0.93

0.06

0.13

−0.44

0.38

 UNC5A

0.92

0.06

0.13

0.06

0.21

 UNC5C

0.91

0.05

0.11

−0.07

0.13

Pr(hypomethylation)

 MAPK1

>0.99

−0.15

0.14

−0.23

0.35

 HRAS

0.97

−0.07

0.06

−0.04

0.41

 EPHA1

0.98

−0.07

0.08

0.24

0.21

 NFATC2

0.91

−0.05

0.05

−0.19

0.39

 NGEF

0.91

−0.05

0.06

0.52

0.39

 NTNG2

0.91

−0.06

0.12

−0.23

0.35

 PLXNB3

0.96

−0.08

0.10

0.43

0.51

 PPP3R2

0.98

−0.10

0.12

<0.01

0.11

 SEMA3B

0.97

−0.10

0.15

−0.60

0.43

 SEMA4A

0.98

−0.16

0.19

<0.01

0.61

 SEMA4G

0.93

−0.05

0.06

0.25

0.51

 SEMA6B

0.98

−0.10

0.11

−0.06

0.41

  1. The corresponding average and standard deviation of difference in DNA methylation and gene expression are also listed.