Table 1 Genetic diversity of the founder and evolved populations determined by ultra-deep sequencing a,b .
From: Constrained evolvability of interferon suppression in an RNA virus
Line | Gene | SNP | Residue | Abundance (%) |
---|---|---|---|---|
Founder | L | G5899A | D105N | 19.8 |
L | G7365A | – | 22.7 | |
L | A9498G | – | 40.6 | |
L | A9584U | E1333V | 30.6 | |
L | A10420C | I1612L | 37.3 | |
L | C11175U | – | 37.0 | |
L | G11217A | – | 37.8 | |
L1 | P | A1898C | M168L | 78.5 |
P | G1900A | M168I | 17.5 | |
P | A2019C | Q208P | 65.7 | |
P | U2077C | – | 78.8 | |
M | C2388A | – | 18.6 | |
G | C4119A | – | 12.8 | |
L | U7326A | – | 14.3 | |
L | C7624U | – | 19.6 | |
L | G9486A | – | 14.2 | |
L | G9591A | – | 14.4 | |
L | C10400A | S1605Y | 19.6 | |
L2 | N | G543U | – | 11.7 |
P | G1900A | M168I | 86.0 | |
M | A2472C | R73S | 11.4 | |
M | A2755G | K168E | 46.2 | |
G | A3716U | E210V | 11.9 | |
G | A4138C | I351L | 12.6 | |
L | G6148U | G188C | 13.9 | |
L | G6972A | – | 11.2 | |
L | U7050C | – | 12.2 | |
L | A7820G | E745G | 13.5 | |
L3 | M | C2639U | P129L | 49.3 |
L | G6188A | R201K | 27.5 | |
L | A6245G | K220R | 14.9 | |
L | A6963U | – | 27.2 | |
L | U10373A | M1596K | 24.1 |