Figure 1 | Scientific Reports

Figure 1

From: Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts

Figure 1

Stable knockdown of lncRNA-ATB inhibits autocrine secretion of TGF-β2 in keloid fibroblast.

(A,B) qRT-PCR analysis of lncRNA-ATB levels in keloid (K) and normal skin (NS) tissues (57 paired samples), as well as in 17 pairs of keloid fibroblasts (KF) and normal fibroblasts (NF); (C) qRT-PCR determination of relative lncRNA-ATB expression levels in KF at 48 h and 72 h after knockdown of lncRNA-ATB with lncRNA-ATB–specific shRNAs (shRNA-ATB-1 and shRNA-ATB-2) compared with a negative control siRNA (shRNA-control); (D) ELISA of relative TGF-β2 expression levels in KF at 48 h and 72 h after knockdown of lncRNA-ATB.

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