Figure 4
From: TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis

Estradiol (E2) and progesterone (P4) regulate hepatic glucose metabolism.
HepG2 and HUH7 cells (2.5 × 105 cells per well) were seeded in 6-well plates and treated with 100 nM E2, 1 μM P4, or E2 plus P4 for 24 h. (A) 2-NBDG uptake. (B) Glucose production. (C) Western blot. *P < 0.05 vs. sex hormone treatment control.