Figure 4: ma-EBOV mouse challenge study with purified fully human polyclonal antibody against Ebola (SAB-139-V2). | Scientific Reports

Figure 4: ma-EBOV mouse challenge study with purified fully human polyclonal antibody against Ebola (SAB-139-V2).

From: Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle

Figure 4

BALB/c mice (n = 10/group) received a single intraperitoneal injection of 100 mg/kg of purified negative control pAbs or 100 mg/kg of SAB-139-V2 24 hr or 48 hr after lethal challenge with 100 PFU ma-EBOV by intraperitoneal route. Kaplan-Meier survival analysis is shown indicating the percentage of surviving mice for 28 days post challenge. A two tailed Fisher’s exact test was used to analyze mouse survival data on day 28.

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