Figure 5: Ionizing radiation can induce the formation of IsoLG-modified proteins in vivo.
From: Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
Mouse pulmonary tissue was obtained 16 weeks after exposure to sham irradiation (A,C) or 16 Gy (B,D). (A,B) IHC D11 ScFv immunostaining, counterstained with methyl green. (C,D) D11 ScFv immunofluorescence (IF) counterstained with DAPI. Random fields are shown. (E) Mean (±SD) immunofluorescence staining was measured at 60× magnification by wide-field microscopy (40 fields per time point obtained from 12 mice). White bar represents 30 μm.
