Table 2 Effects of normal, sham, control (saline), 5f, epalrestat and edaravone treatments on the percentage of embryo death, NTD and body weight.

From: Bioactivity Focus of α-Cyano-4-hydroxycinnamic acid (CHCA) Leads to Effective Multifunctional Aldose Reductase Inhibitors

Items

Treatment (n = 20)

Control

Glucose (0.4 mmol/egg)

Model

CL 10 nM

CM 100 nM

CH 1 μM

Epalrestat 1 μM

Edaravone 0.1 nM

Death (/n)

8.7%

40.0%

35.0%

30.0%

25.0%

25.0%

20.0%

NTD (/survival)

1.6%

58.3%

46.20%

35.7%

20.0%

26.7%

18.8%

Body weight (mg)

310.4 ± 6.3

286.2 ± 8.5 **

291.3 ± 10.2

295.9 ± 13.2 #

307.9 ± 10.5 ##

300.1 ± 3.6 #

310.8 ± 11.6 ##

  1. *P < 0.05, **P < 0.01 vs. control.
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