Figure 7: The predicted binding mode of plasiatine (1) in the catalytic domain of Shp2 (PDB entry: 4PVG). | Scientific Reports

Figure 7: The predicted binding mode of plasiatine (1) in the catalytic domain of Shp2 (PDB entry: 4PVG).

From: Plasiatine, an Unprecedented Indole–Phenylpropanoid Hybrid from Plantago asiatica as a Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2

Figure 7

(A) The binding mode revealed by molecular docking. (B) Interaction details of plasiatine (1) and Shp2. Plasiatine (1) (cyan carbon) and residues in contact with 1 (blue carbon) were presented in sticks. H-bond interactions were highlighted in yellow dashed lines.

Back to article page