Figure 3
From: Baicalein pretreatment reduces liver ischemia/reperfusion injury via induction of autophagy in rats
Baicalein decreases liver injury after I/R through induction of Autophagy.
Rats were pretreated with 3-MA (30 mg/kg, IP) 0.5 h prior to baicalein treatment (100 mg/kg, IP) and sacrificed at 6 h after reperfusion. (a) Western blot analysis of LC3B protein expression in the ischemic lobes. (b) Densitometric analysis of LC3B-II expression. (c) Quantification of serum ALT and AST levels. (d) Representative images of liver I/R injury (Original magnification × 400, Scale bars 100 μm). (e) Quantification of histological damage. Data are shown as the mean ± SD, n = 6 per group.
