Figure 4: Misfolded TTR antibody labels TTR amyloids in vivo. | Scientific Reports

Figure 4: Misfolded TTR antibody labels TTR amyloids in vivo.

From: Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and therapeutic for TTR amyloidoses

Figure 4

Formalin fixed paraffin embedded (FFPE) cardiac tissue sections from a patient with I84S TTR mutation were labeled using misTTR (dark brown, A), a non-specific isotype control antibody (dark brown, B), or the amyloid specific dyes Thioflavin T or Congo Red (green C, red D, green E).

Back to article page