Table 1 miRNAs that putatively regulate NR4A2 through its 3′ UTR.
From: The orphan nuclear receptor NR4A2 is part of a p53–microRNA-34 network
Rank | miRNA ID | Log2 fold change | P-value | TargetScan | miRanda | PicTar | Other predicted NR4A genes | Other targets |
|---|---|---|---|---|---|---|---|---|
1 | hsa-miR-335 | −0.47549 ± 0.0223 | <0.0001 | No | No | No | NR4A3 | BCL2L2, SOX4, RB1, RUNX2 |
2 | hsa-miR-34c | −0.4752 ± 0.1028 | <0.0001 | Yes | Yes | Yes | — | BCL2, CCND1, CDK4/6, FRA1, MET, MYC, MYCN, SIRT1, SNAI1 |
3 | hsa-miR-144 | −0.44443 ± 0.0696 | <0.0001 | No | No | No | NR4A3 | NOTCH1, PTEN, TGFB1 |
4 | hsa-miR-214 | −0.37908 ± 0.0942 | 0.0002 | No | Yes | Yes | NR4A1 | BCL2L2, EZH2, PTEN, TWIST1 |
5 | hsa-miR-191 | −0.37123 ± 0.1471 | 0.0002 | No | No | No | — | CDK6, SOX4 |
6 | hsa-miR-15a | −0.36165 ± 0.0343 | 0.0004 | No | No | No | NR4A1, NR4A3 | BCL2, CCND1, CCND2, CCNE1, CRKL, VEGFA |
7 | hsa-miR-155 | −0.36052 ± 0.0926 | 0.0004 | No | No | No | NR4A3 | APC, FOXO3, MLH1, RUNX2, SMAD1, SMAD2, SMAD5 |
8 | hsa-miR-20a | −0.35512 ± 0.0296 | 0.0005 | Yes | Yes | Yes | NR4A3 | CCND1, CDKN1A, E2F1, HIF1A, KIT, PTEN |
9 | hsa-miR-25 | −0.35227 ± 0.128 | 0.0006 | No | No | No | NR4A3 | BCL2L11, CDH1, EZH2, MDM2, TP53 |
17 | hsa-miR-132 | −0.296850 ± 0.1684 | 0.0086 | Yes | Yes | Yes | — | CDKN1A, NR4A2, RB1, SIRT1 |
