Figure 3: IL-17A neutralization disturbed the migration of neutrophils.
From: Seminal plasma induces inflammation in the uterus through the γδ T/IL-17 pathway
(a) The percentage of neutrophils in the CD45-gated population in the uterus was measured at D0.5. The numbers represent the percentage of the population within the indicated gates. (b) Absolute numbers of neutrophils in the uterus were measured at D0.5. The data are shown as the mean ± S.E.M. from four (Isotype) or eight (IL-17A blocking) independent experiments and independent t-tests. (c) Ly6G stained neutrophils in the uterus were analysed by immunohistochemistry at D1 and virgin. The arrow indicates Ly6G positive cells. The photomicrographs are representative of three mice in each group. Panels ii, iii, v, vi and viii, ix are higher magnifications of different areas marked by the black rectangles in panels i, iv and vii. LE, luminal epithelium; S, stroma, VE, vessels epithelium; GE, gland epithelium. Scale bar: 500 μm (I, iv and vii) and 50 μm (ii, iii, v, vi and viii, ix).
