Figure 3: Mmp11-Tg mice are resistant to HFD-induced metabolic syndrome.
From: Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch
(a) Weight gain progression during 6 weeks of a HFD (n = 13/group) and fat mass measurement at 6 weeks (n = 8–9/group); (b) IPGTT (left panel) and IPIST (right panel) tests and AUC (n = 8–10/group) after 6 weeks of a HFD; (c) HE and TEM analyses of the WAT (left panel) and BAT (right panel) in Mmp11-Tg and WT mice under HFD; (d) Mean daily food intake over 4 days (n = 8–9/group) and total energy expenditure (TEE) quantification at week 5 of the diet (n = 8/group); (e) Metabolic gene expression profile in the WAT (n = 8/group).
