Table 3 Life course multiple regression analyses for father’s occupational position and inflammatory status.
Variables | Levels | Model A | Model B-1 | Model B-2 | Model C | Fully Adjusted Model | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | ||
(A) Plasma concentration of CSF3 | |||||||||||
Father’s occupational position | Manual | 0.29 (0.09) | 0.002 | 0.27 (0.10) | 0.008 | 0.29 (0.10) | 0.004 | 0.28 (0.10) | 0.008 | 0.28 (0.10) | 0.007 |
Participant’s education | Low | 0.03 (0.10) | 0.733 | – | – | 0.04 (0.11) | 0.742 | 0.02 (0.12) | 0.868 | ||
Household’s highest occupation | Manual | 0.01 (0.10) | 0.916 | −0.01 (0.11) | 0.957 | −0.02 (0.11) | 0.862 | ||||
BMI | 0.02 (0.01) | 0.230 | |||||||||
Smoking status | Former | −0.01 (0.12) | 0.917 | ||||||||
Current | −0.01 (0.12) | 0.608 | |||||||||
Alcohol | 0.001 (0.003) | 0.644 | |||||||||
(B) Inflammatory score | |||||||||||
Father’s occupational position | Manual | 1.96 (0.89) | 0.029 | 2.88 (0.97) | 0.003 | 2.64 (0.93) | 0.005 | 3.08 (0.98) | 0.002 | 2.93 (1.00) | 0.004 |
Participant’s education | Low | −2.22 (0.98) | 0.024 | – | – | −1.54 (1.08) | 0.156 | −1.5 (1.10) | 0.174 | ||
Household’s highest occupation | Manual | −2.22 (0.97) | 0.023 | −1.56 (1.07) | 0.149 | −1.49 (1.09) | 0.174 | ||||
BMI | −0.07 (0.13) | 0.617 | |||||||||
Smoking status | Former | −0.62 (1.16) | 0.594 | ||||||||
Current | −0.57 (1.16) | 0.621 | |||||||||
Alcohol | −0.02 (0.03) | 0.433 | |||||||||
(C) Principal component 1 | |||||||||||
Father’s occupational position | Manual | −0.60 (0.45) | 0.182 | −1.05 (0.49) | 0.031 | −0.84 (0.47) | 0.074 | −1.10 (0.49) | 0.026 | −1.06 (0.50) | 0.034 |
Participant’s education | Low | 1.10 (0.49) | 0.025 | – | – | 0.93 (0.54) | 0.088 | 0.95 (0.55) | 0.086 | ||
Household’s highest occupation | Manual | 0.79 (0.49) | 0.104 | 0.39 (0.54) | 0.466 | 0.40 (0.55) | 0.462 | ||||
BMI | −0.01 (0.07) | 0.856 | |||||||||
Smoking status | Former | 0.27 (0.58) | 0.639 | ||||||||
Current | 0.48 (0.58) | 0.411 | |||||||||
Alcohol | 0.01 (0.01) | 0.637 |