Figure 7 | Scientific Reports

Figure 7

From: Reversal of the Detrimental Effects of Post-Stroke Social Isolation by Pair-Housing is Mediated by Activation of BDNF-MAPK/ERK in Aged Mice

Figure 7

A representative mosaic image of a mouse brain section (10 × magnifications) for GFAP expression 4 weeks after MCAO.

Immunostaining with GFAP (red) showed that GFAP + cells were activated at the site of infarction in both stroke groups. Dotted lines show that dense GFAP expression (the glial scar) was confined to the striatal region in ST-PH mice while it was larger and spread to both the striatum and cortex (n = 4 per group) in ST-ISO mice.

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