Table 2 Meta-analysis of the association between MTHFR C677T polymorphism and MM risk.
From: A Mendelian Randomization Study of Plasma Homocysteine and Multiple Myeloma
Genetic models | OR (95% CI) | P value | Model | I2 value (%) |
|---|---|---|---|---|
T vs. C | 1.17 (1.02, 1.34) | 0.03 | Random | 47 |
TT vs. CC | 1.16 (0.98, 1.37) | 0.08 | Fixed | 29 |
TC vs. CC | 1.18 (0.96, 1.45) | 0.12 | Random | 46 |
TT + TC vs. CC | 1.22 (1.00, 1.48) | 0.05 | Random | 47 |
TT vs. TC + CC | 1.13 (0.98, 1.32) | 0.10 | Fixed | 20 |
