Table 4 Reduction in the cumulated number of infectious individuals following vaccination of 85% newborns at birth (strategy F) or combination of routine vaccination (42.5%) and pulse vaccination (42.5%) according to different spatial vaccination strategies (A, B, C, D, E).

From: Hand, Foot, and Mouth Disease in China: Critical Community Size and Spatial Vaccination Strategies

Strategy

Red 5-Years (%) ± 95%

Red 20-Years (%) ± 95%

Random (A)

46.1 [44.0;48.2]

48.1 [47.7;48.5]

Close-CCS (B)

38.2 [35.7;40.7]

43.3 [42.8;43.8]

Large(C)

47.7 [45.1;50.2]

49.2 [45.5;52.9]

Small(D)

37.3 [35.2;39.5]

42.4 [42.0;42.9]

High Prevalence (E)

48.6 [46.3;50.8]

52.4 [52.0;52.9]

Routine 85% (F)

71.7 [70.0;73.4]

77.8 [77.3;78.2]

Routine non-NIP (F * )

39.4 [23.3;56.6]

40.7 [25.2;60.0]

  1. Coverage rate = 85% and vaccine efficacy = 94.8% in each vaccinated county.
  2. *The confidence interval for simulations of vaccination outside of China’s National Immunization Program (non-NIP) are based on the range of estimates found from the existing literature (Supplementary Information, Table SIV 1).
Back to article page