Table 1 Performance of MeltPro for detecting rifampin-resistance.
From: Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Pilot | MeltPro | DST | Total | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|---|---|---|
R | S | |||||||
Shandong | R | 107 | 15 | 122 | 96.4(91.1–98.6) | 97.6(96.0–98.2) | 87.7(80.7–92.4) | 99.2(98.2–99.7) |
S | 4 | 601 | 605 | |||||
Total | 111 | 616 | 727 | |||||
Guangzhou | R | 155 | 17 | 172 | 92.8(87.9–95.8) | 97.4(95.8–98.4) | 90.1(84.7–93.7) | 98.2(96.8–99.0) |
S | 12 | 630 | 642 | |||||
Total | 167 | 647 | 814 | |||||
Total | R | 262 | 32 | 294 | 94.2(90.9–96.4) | 97.5(96.4–98.2) | 89.1(85.0–92.2) | 98.7(97.9–99.2) |
S | 16 | 1231 | 1247 | |||||
Total | 278 | 1263 | 1541 | |||||
