Table 2 Performance of MeltPro for detecting isoniazid-resistance.
From: Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Pilot | MeltPro | DST | Total | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|---|---|---|
R | S | |||||||
Shandong | R | 134 | 13 | 147 | 86.4(80.2–91.0) | 97.7(96.2–98.7) | 91.2(85.5–94.8) | 96.4(94.5–97.6) |
S | 21 | 559 | 580 | |||||
Total | 155 | 572 | 727 | |||||
Guangzhou | R | 197 | 10 | 207 | 83.8(78.6–88.0) | 98.3(96.8–99.1) | 95.2(91.3–97.4) | 93.7(91.5–95.4) |
S | 38 | 569 | 607 | |||||
Total | 235 | 579 | 814 | |||||
Total | R | 331 | 23 | 354 | 84.9(81.0–88.1) | 98.0(97.0–98.7) | 93.5(90.4–95.6) | 95.0(93.6–96.1) |
S | 59 | 1128 | 1187 | |||||
Total | 390 | 1151 | 1541 | |||||
