Table 3 Performance of MeltPro for detecting multi-drug resistance.
From: Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Pilot | MeltPro | DST | Total | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|---|---|---|
R | S | |||||||
Shandong | R | 85 | 14 | 99 | 87.6(79.6–92.8) | 97.8(96.3–98.7) | 85.9(77.6–91.4) | 98.1(96.7–98.9) |
S | 12 | 616 | 628 | |||||
Total | 97 | 630 | 727 | |||||
Guangzhou | R | 130 | 16 | 146 | 86.1(79. 7–90.7) | 97.6(96.1–98.5) | 89.0(82.9–93.1) | 96.9(95.2–97.9) |
S | 21 | 647 | 668 | |||||
Total | 151 | 663 | 814 | |||||
Total | R | 215 | 30 | 245 | 86.7(81.9–90.4) | 97.7(96.7–98.4) | 87.8(83.1–91.3) | 97.4(96.4–98.2) |
S | 33 | 1263 | 1296 | |||||
Total | 248 | 1293 | 1541 | |||||
