Table 4 Performance of MeltPro for detecting ofloxcin-resistance.
From: Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Pilot | MeltPro | DST | Total | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|---|---|---|
R | S | |||||||
Shandong | R | 99 | 18 | 117 | 86.1(78.6–91.2) | 97.1(95.4–98.1) | 84.6(77.0–90.0) | 97.4(95.8–98.4) |
S | 16 | 594 | 610 | |||||
Total | 115 | 612 | 727 | |||||
Guangzhou | R | 106 | 7 | 113 | 80.9(73.3–86.7) | 99.0(97.9–99.5) | 93.8(87.8–97.0) | 96.4(94.8–97.6) |
S | 25 | 676 | 701 | |||||
Total | 131 | 683 | 814 | |||||
Total | R | 205 | 25 | 230 | 83.3(78.2–87.5) | 98.1(97.2–98.7) | 89.1(84.4–92.5) | 96.9(95.8–97.7) |
S | 41 | 1270 | 1311 | |||||
Total | 246 | 1295 | 1541 | |||||
