Table 5 Performance of MeltPro for detecting amikacin-resistance.
From: Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Pilot | MeltPro | DST | Total | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|---|---|---|
R | S | |||||||
Shandong | R | 19 | 8 | 27 | 76.0(56.6–88.5) | 98.9(97.8–99.4) | 70.4(51.5–84.2) | 99.1(98.1–99.6) |
S | 6 | 694 | 700 | |||||
Total | 25 | 702 | 727 | |||||
Guangzhou | R | 20 | 12 | 32 | 74.1(55.3–86.8) | 98.5(97.4–99.1) | 62.5(45.2–77.1) | 99.1(98.2–99.6) |
S | 7 | 775 | 782 | |||||
Total | 27 | 787 | 814 | |||||
Total | R | 39 | 20 | 59 | 75.0(61.8–84.8) | 98.7(97.9–99.1) | 66.1(53.4–76.9) | 99.1(98.5–99.5) |
S | 13 | 1469 | 1482 | |||||
Total | 52 | 1489 | 1541 | |||||
