Table 6 Performance of MeltPro for detecting kanamycin-resistance.
From: Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Pilot | MeltPro | DST | Total | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|---|---|---|
R | S | |||||||
Shandong | R | 22 | 5 | 27 | 81.5(63.3–91.8) | 99.3(98.3–99.7) | 81.5(63.3–91.8) | 99.3(98.3–99.7) |
S | 5 | 695 | 700 | |||||
Total | 27 | 700 | 727 | |||||
Guangzhou | R | 25 | 7 | 32 | 53.2(39.2–66.7) | 99.1(98.1–99.6) | 78.1(61.2–89.0) | 97.2(95.8–98.1) |
S | 22 | 760 | 782 | |||||
Total | 47 | 767 | 814 | |||||
Total | R | 47 | 12 | 59 | 63.5(52.1–73.6) | 99.2(98.6–99.5) | 79.7(67.7–88.0) | 98.2(97.4–98.7) |
S | 27 | 1455 | 1482 | |||||
Total | 74 | 1467 | 1541 | |||||
