Table 8 Performance of MeltPro for detecting extensive drug-resistance.
From: Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro TB assay in China
Pilot | MeltPro | DST | Total | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|---|---|---|
R | S | |||||||
Shandong | R | 16 | 3 | 19 | 88.9(67.2–96.9) | 99.6(98.8–99.8) | 84.2(62.4–94.5) | 99.7(99.0–99.9) |
S | 2 | 706 | 708 | |||||
Total | 18 | 709 | 727 | |||||
Guangzhou | R | 14 | 3 | 17 | 58.3(38.8–75.5) | 99.6(98.9–99.9) | 82.4(59.0–93.8) | 98.8(97.7–99.3) |
S | 10 | 787 | 797 | |||||
Total | 24 | 790 | 814 | |||||
Total | R | 30 | 6 | 36 | 71.4(56.4–82.8) | 99.6(99.1–99.8) | 83.3(68.1–92.1) | 99.2(98.6–99.5) |
S | 12 | 1493 | 1505 | |||||
Total | 42 | 1499 | 1541 | |||||
