Figure 4
Milk composition and yield effects at the chromosome 5 locus.
Manhattan plots (4A) showing association of sequence variants for multiple milk composition and yield traits at the MGST1 locus (chr5:93920738-93970738; MGST1 gene structure is indicated in each panel). The number of animals included in these analyses range from 64,141 to 51,120 between traits (Table 2). Figure 4B shows scatter plots of –log10 P-values where the y-axis represents the milk fat percentage association statistic and the x-axes represent association for the other milk traits. These plots indicate the rank order of variants relative to milk fat percentage, with the strong correlation of signals suggesting a common genetic basis for all traits. Variants are coloured according to their linkage disequilibrium (LD) with the top milk fat percentage associated SNP g.93945738C > T, with LD reflecting values calculated within each respective population.
