Table 1 Nanoparticle Characterization.

From: Distribution of Systemically Administered Nanoparticles Reveals a Size-Dependent Effect Immediately following Cardiac Ischaemia-Reperfusion Injury

Nanoparticle

Core Diameter, TEM (nm ± SD)

Hydrodynamic Size, DLS (nm)

Zeta potential (mV)

20 nm PS

22.1 ± 2.7

32.4 ± 0.2

−31.8 ± 0.5

20 nm PEG-PS

65.3 ± 0.3

−3.2 ± 1.1

100 nm PS

96.6 ± 6.2

121.8 ± 0.5

−37.0 ± 1.5

100 nm PEG-PS

136.4 ± 1.5

−3.9 ± 0.6

200 nm PS

188.1 ± 7.2

212.3 ± 1.1

−55.2 ± 2.4

200 nm PEG-PS

225.8 ± 1.7

−3.7 ± 0.9

500 nm PS

454.1 ± 15.8

500.7 ± 4.4

−42.7 ± 1.3

500 nm PEG-PS

548.1 ± 7.3

−3.4 ± 0.2

1 μm PS

1010.6 ± 42.0

1028.1 ± 75.1

−51.0 ± 1.3

1 μm PEG-PS

1099.0 ± 21.7

−4.4 ± 0.1

2 μm PS

1970.0 ± 93.8

2339.0 ± 52.1

−52.1 ± 3.7

2 μm PEG-PS

2518.3 ± 121.9

−4.3 ± 0.2

  1. Core diameter was measured by TEM, and hydrodynamic size was measured by DLS. Hydrodynamic size increased compared to the core diameter, and zeta potential became less negative following PEG modification, as expected.
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