Table 2 Direct comparison for COR, TC, fatigue, hot flush and BCS.
Outcome | Events | Total | Events | Total | OR (95% CI) | |
---|---|---|---|---|---|---|
Let vs. Exe (<20wks) | COR | 112 | 155 | 91 | 148 | 1.63 (1.01 to 2.64) |
TC | 149 | 155 | 136 | 148 | 2.09 (0.79 to 5.54) | |
Fatigue | 14 | 155 | 11 | 148 | 1.23 (0.54 to 2.81) | |
Hot flush | 43 | 155 | 22 | 148 | 2.47 (1.30 to 4.70) | |
BCS | 11 | 127 | 17 | 124 | 0.60 (0.27 to 1.33) | |
Let vs. Exe (<20wks)+Cel | COR | 17 | 28 | 18 | 30 | 1.03 (0.36 to 2.95) |
TC | 28 | 28 | 29 | 30 | 2.90 (0.11 to 74.13) | |
Fatigue | 4 | 28 | 3 | 30 | 1.50 (0.30 to 7.39) | |
Hot flush | 19 | 28 | 6 | 30 | 8.44 (2.55 to 27.91) | |
BCS | – | – | – | – | – | |
Let vs. Let+Eve | COR | 78 | 132 | 94 | 138 | 0.68 (0.41 to 1.11) |
TC | 90 | 132 | 112 | 138 | 0.50 (0.28 to 0.87) | |
Fatigue | 6 | 132 | 17 | 138 | 0.34 (0.13 to 0.89) | |
Hot flush | 22 | 132 | 15 | 138 | 1.64 (0.81 to 3.32) | |
BCS | – | – | – | – | – | |
Let vs. CT | COR | 20 | 22 | 17 | 22 | 2.94 (0.50 to 17.14) |
TC | 20 | 22 | 20 | 22 | 1.00 (0.13 to 7.81) | |
Fatigue | 10 | 22 | 7 | 22 | 1.79 (0.52 to 6.10) | |
Hot flush | 9 | 22 | 2 | 22 | 6.92 (1.29 to 37.29) | |
BCS | 4 | 22 | 1 | 22 | 4.67 (0.48 to 45.62) | |
Let vs. Tam | COR | 85 | 154 | 61 | 170 | 2.20 (1.41 to 3.44) |
TC | 153 | 154 | 169 | 170 | 0.91 (0.06 to 14.60) | |
Fatigue | 8 | 154 | 8 | 170 | 1.11 (0.41 to 3.03) | |
Hot flush | 31 | 154 | 41 | 170 | 0.79 (0.47 to 1.34) | |
BCS | 69 | 154 | 60 | 170 | 1.49 (0.95 to 2.33) | |
Let vs. Ana | COR | 95 | 127 | 85 | 123 | 1.33 (0.76 to 2.31) |
TC | 121 | 127 | 114 | 123 | 1.59(0.55 to 4.61) | |
Fatigue | 10 | 127 | 9 | 123 | 1.08 (0.42 to 2.76) | |
Hot flush | 24 | 127 | 18 | 123 | 1.36 (0.70 to 2.65) | |
BCS | 11 | 127 | 24 | 123 | 0.39 (0.18 to 0.84) | |
Ana vs. Ana+Gef | COR | 48 | 79 | 52 | 109 | 1.70 (0.94 to 3.05) |
TC | 74 | 85 | 95 | 121 | 1.84 (0.85 to 3.97) | |
Fatigue | 8 | 85 | 5 | 121 | 2.41 (0.76 to 7.64) | |
Hot flush | 11 | 85 | 7 | 121 | 2.42 (0.90 to 6.53) | |
BCS | 27 | 85 | 51 | 121 | 0.64 (0.36 to 1.14) | |
Ana vs. Ana+Tam | COR | 42 | 113 | 43 | 109 | 0.91 (0.53 to 1.56) |
TC | 106 | 113 | 100 | 109 | 1.36 (0.49 to 3.80) | |
Fatigue | 6 | 113 | 8 | 109 | 0.71 (0.24 to 2.11) | |
Hot flush | 20 | 113 | 30 | 109 | 0.57 (0.30 to 1.07) | |
BCS | 21 | 113 | 11 | 109 | 2.03 (0.93 to 4.45) | |
Outcome | Events | Total | Events | Total | OR (95% CI) | |
Ana vs. Tam | COR | 123 | 276 | 99 | 259 | 1.30 (0.92 to 1.83) |
TC | 308 | 341 | 302 | 331 | 0.89 (0.53 to 1.51) | |
Fatigue | 11 | 341 | 22 | 331 | 0.47 (0.22 to 0.98) | |
Hot flush | 39 | 341 | 44 | 331 | 0.84 (0.53 to 1.33) | |
BCS | 82 | 255 | 45 | 228 | 1.95 (1.26 to 3.02) | |
Ana vs. Exe (<20wks) | COR | 85 | 123 | 78 | 124 | 1.32 (0.78 to 2.24) |
TC | 114 | 123 | 114 | 124 | 1.11 (0.44 to 2.84) | |
Fatigue | 9 | 123 | 10 | 124 | 0.90 (0.35 to 2.30) | |
Hot flush | 18 | 123 | 10 | 124 | 1.95 (0.86 to 4.42) | |
BCS | 24 | 123 | 17 | 124 | 1.53 (0.77 to 3.01) | |
Tam vs. Tam+Ana | COR | 39 | 108 | 43 | 109 | 0.87 (0.50 to 1.50) |
TC | 101 | 108 | 100 | 109 | 1.30 (0.47 to 3.62) | |
Fatigue | 8 | 108 | 8 | 109 | 1.01 (0.36 to 2.80) | |
Hot flush | 28 | 108 | 30 | 109 | 0.92 (0.51 to 1.68) | |
BCS | 8 | 108 | 11 | 109 | 0.71 (0.27 to 1.85) | |
Exe (<20wks) vs. Exe (≥20wks) | COR | 11 | 26 | 12 | 25 | 0.79 (0.26 to 2.40) |
TC | 26 | 26 | 25 | 26 | 3.12 (0.12 to 80.12) | |
Fatigue | – | 26 | – | 25 | – | |
Hot flush | – | 26 | – | 25 | – | |
BCS | 4 | 26 | 1 | 25 | 4.36 (0.45 to 42.08) | |
Exe (<20wks) vs.Exe (<20wks)+Cel | COR | 13 | 24 | 18 | 30 | 0.79 (0.27 to 2.33) |
TC | 22 | 24 | 29 | 30 | 0.38 (0.03 to 4.46) | |
Fatigue | 1 | 24 | 3 | 30 | 0.39 (0.04 to 4.02) | |
Hot flush | 12 | 24 | 6 | 30 | 4.00 (1.20 to 13.28) | |
BCS | – | – | – | – | – |