Figure 4: GO (gene ontology) analysis of the differentially expressed proteins in ETEC-induced diarrheal piglets.

The differentially expressed proteins among diarrheal piglets, recovery piglets, resistant piglets and control piglets were characterized by iTRAQ-based proteomics, and then the functional annotations of 92 differentially expressed proteins were conducted with GO analysis. A total of 92 differentially expressed proteins were selected based on the inclusion standard that the protein is differently expressed between diarrheal piglets and control piglets, meanwhile the level of proteins in resistant piglets or recovery piglets is closer to control piglets, compared to diarrheal piglets. iTRAQ: isobaric tags for relative and absolute quantitation; ETEC: Enterotoxigenic Escherichia coli.