Figure 3
From: Analysis of crystal structure of Arabidopsis MPK6 and generation of its mutants with higher activity
Comparison of the glycine-rich loop, MKI and L16 loop in MPK6 (red) with those in ERK2 (green) and p38 (yellow).
(A) The local superposition of the glycine-rich loop in MPK6 with that in ERK2 and p38 showed that the glycine-rich loop in MPK6 was bent towards the ATP-binding pocket. (B) The local superposition of the MKI in MPK6 with that in ERK2 and p38 showed the dramatic conformational changes in the α1L14 position of MPK6. (C) The local superposition of the L16 loop in MPK6 with that in ERK2 and p38 showed large conformational changes between the structures.
