Figure 7
From: Osthole inhibits histamine-dependent itch via modulating TRPV1 activity
Osthole directly modulates TRPV1 activity.
(A) Osthole could completely block the response induced by capsaicin. After 10-minutes washout, the response to capsaicin-induced recovered. (B) The representative trace showed the intracellular calcium influx that capsaicine used alone and capsaicine together with vehcle (1% DMSO). (C) The normalized fluorescence intensities of osthole to inhibit capsaicine -induced calcium influx.
