Table 3 Joint testing of association with schizophrenia and smoking traits.
From: Genetic Relationship between Schizophrenia and Nicotine Dependence
SNP | Chr | Location (bp) | Z (ND) | Z (SCZ) | P-value | Q-value | Gene symbol | # markers |
|---|---|---|---|---|---|---|---|---|
COT | ||||||||
rs798015 | 1 | 117,320,907 | −3.71 | −3.69 | 5.08E-08 | 0.0020 | DA376252 | 3 |
rs9850756 | 3 | 18,905,739 | −3.71 | 3.62 | 8.72E-08 | 0.0030 | DA733783 | 1 |
rs709071 | 3 | 191,426,311 | −3.46 | 3.51 | 2.85E-07 | 0.0081 | – | 1 |
rs12640124 | 4 | 118,775,172 | 3.61 | −3.50 | 2.12E-07 | 0.0063 | BX089737 | 3 |
rs2442720 | 6 | 31,320,277 | −3.49 | 4.62 | 2.26E-07 | 0.0067 | HLA-B | 1 |
rs11779524 | 8 | 8,618,613 | 3.85 | 3.81 | 1.89E-08 | 0.0008 | CF594265 | 4 |
rs56235824 | 9 | 11,039,320 | 3.44 | 3.55 | 3.38E-07 | 0.0090 | – | 1 |
rs11788261 | 9 | 138,611,139 | 3.80 | 3.51 | 1.95E-07 | 0.0060 | KCNT1 | 2 |
rs8042374 | 15 | 78,908,032 | 7.69 | 7.04 | 3.48E-24 | 1.68E-17 | CHRNA5/CHRNA3/CHRNB4 | 270 |
rs6650723 | 18 | 53,524,269 | 3.76 | 3.51 | 2.07E-07 | 0.0062 | DA696352/LOC101927273 | 5 |
rs7228837 | 18 | 75,817,606 | 4.23 | 3.65 | 6.64E-08 | 0.0024 | LINC01029 | 19 |
FTND | ||||||||
rs56335113 | 1 | 30,427,639 | 3.80 | 5.85 | 2.02E-08 | 0.0021 | – | 10 |
rs36025078 | 2 | 155,883,716 | −3.90 | −3.59 | 1.13E-07 | 0.0061 | – | 1 |
rs188499496 | 3 | 38,450,183 | −3.93 | −3.62 | 8.82E-08 | 0.0050 | XYLB | 2 |
rs11917643 | 3 | 64,171,754 | 3.62 | −4.17 | 8.41E-08 | 0.0048 | PRICKLE2 | 6 |
rs76923559 | 4 | 34,053,926 | −3.93 | −3.79 | 2.35E-08 | 0.0023 | LOC101928622 | 3 |
rs147093127 | 5 | 152,086,293 | 3.67 | 4.01 | 5.70E-08 | 0.0037 | LINC01470 | 1 |
rs9322751 | 6 | 104,015,759 | −3.51 | −3.54 | 2.03E-07 | 0.0089 | HY157071 | 6 |
rs4994764 | 7 | 1,928,662 | −3.90 | −4.32 | 9.17E-09 | 0.0012 | MAD1L1 | 18 |
rs3910267 | 11 | 130,810,282 | −3.84 | 5.71 | 1.50E-08 | 0.0018 | SNX19 | 21 |
rs147144681 | 15 | 78,900,908 | −7.62 | −5.55 | 7.85E-16 | 5.66E-09 | CHRNA5/CHRNA3/CHRNB4 | 106 |
TFC | ||||||||
rs4658015 | 1 | 196,053,435 | 3.51 | 3.36 | 5.91E-07 | 0.0094 | – | 1 |
rs1069267 | 3 | 38,435,023 | −3.63 | −4.43 | 8.02E-08 | 0.0015 | XYLB | 3 |
rs11722779 | 4 | 103,827,488 | 4.22 | −4.30 | 6.00E-10 | 0.0001 | MANBA/UBE2D3/SLC9B2 | 315 |
rs2717737 | 8 | 18,459,343 | −3.36 | 3.73 | 6.05E-07 | 0.0096 | PSD3 | 1 |
rs13264022 | 8 | 21,293,046 | 3.50 | 4.01 | 2.16E-07 | 0.0038 | DA902558 | 15 |
rs7959287 | 12 | 103,601,638 | 3.84 | 4.49 | 1.54E-08 | 0.0003 | – | 5 |
rs9594516 | 13 | 41,849,360 | 3.64 | 3.77 | 7.33E-08 | 0.0014 | MTRF1 | 1 |
rs112531467 | 13 | 43,865,047 | −3.66 | 3.52 | 1.86E-07 | 0.0033 | ENOX1 | 1 |
rs181676509 | 14 | 104,242,531 | −3.67 | −3.98 | 5.73E-08 | 0.0011 | C14ORF2 | 15 |
rs147144681 | 15 | 78,900,908 | −5.50 | −5.55 | 1.49E-15 | 1.08E-08 | CHRNA5/CHRNA3/CHRNB4 | 72 |
rs17665477 | 16 | 6,700,889 | −3.69 | 3.80 | 5.16E-08 | 0.0010 | RBFOX1 | 11 |
rs12462853 | 19 | 5,538,936 | 3.45 | −3.39 | 4.82E-07 | 0.0078 | TINCR | 2 |
rs62202174 | 20 | 20,461,125 | −3.38 | −4.24 | 5.26E-07 | 0.0085 | RALGAPA2 | 1 |
rs5758274 | 22 | 41,664,539 | 3.64 | −4.45 | 7.43E-08 | 0.0014 | RANGAP1 | 1 |
rs8135804 | 22 | 42,334,660 | 3.40 | 3.57 | 4.54E-07 | 0.0074 | CENPM | 12 |
