Figure 1: Validation of miRNA expression in mouse tissues in response to irradiation.
From: Low-dose irradiation promotes Rad51 expression by down-regulating miR-193b-3p in hepatocytes
A qRT-PCR validation of differentially expressed miRNAs (listed in Table 1) was performed. Mice were irradiated with 0.01 Gy (6.5 mGy/h). Six hours post-irradiation, miRNA expression was evaluated in the spleens (A), livers (B), kidneys (C), and lungs (D) and reported as fold-change differences relative to compared with the sham-irradiated controls. The mouse U6 and 5S genes were used as the normalization factors. The data shown are the mean ± S.D. (n = 5). Statistically significant differences between the non-irradiated and irradiated samples are indicated (*p < 0.05, **p < 0.01, and ***p < 0.001 vs. the sham group).
