Figure 3

VLDL production and plasma TG concentrations in Pemt^−/− and Tgh^−/−/Pemt^−/− mice fed chow and HFD.

(a) Plasma TG levels in WT, Pemt^−/− and Tgh^−/−/Pemt^−/− mice fed chow. (b) Plasma TG levels in WT, Pemt^−/− and Tgh^−/−/Pemt^−/− mice after 1 week of HFD. (c) Plasma TG levels in WT, Pemt^−/− and Tgh^−/−/Pemt^−/− mice after 10 weeks of HFD. (d) In vivo VLDL-TG secretion in WT, Tgh^−/−, Pemt^−/− and Tgh^−/−/Pemt^−/− mice after 10 weeks of HFD. n = 5,6. Data are mean ± SEM, **P < 0.01, ***P < 0.001 vs WT control.